China Gold Supplier for Cdmo In Pharma - Ene reductase (ERED) – SyncoZymes
China Gold Supplier for Cdmo In Pharma - Ene reductase (ERED) – SyncoZymes Detail:
ES-EREDs catalyze various substrate types because of wide spectrum of substrates. In general, the C=C of α, β -unsaturated compounds with electron-absorbing groups (including ketone aldehyde, nitro groups, carboxylic acids, esters, anhydride, lactones, imines, etc.) are easily reduced by ES-EREDs, but the unactivated double bonds not.
There are 46 kinds of ERED enzyme products (Number as ES-ERED-101~ES-ERED-146) developed by SyncoZymes.
Catalytic mechanism:
| Enzymes | Product Code | Specification |
| Enzyme Powder | ES-ERED-101~ ES-ERED-146 | a set of 46 Ene Reductases, 50 mg each 46 items * 50mg / item, or other quantity |
| Screening Kit (SynKit) | ES-ERED-4600 | a set of 46 Ene Reductases, 50 mg each 46 items * 50mg / item, or other quantity |
★ High substrate specificity.
★ Strong chiral selectivity.
★ High conversion.
★ Less by-products.
★ Mild reaction conditions.
★ Environmentally friendly.
★ High safety.
➢ Normally, the reaction system should include substrate, buffer solution (optimum reaction pH), coenzymes(NAD(H) or NADP(H) ), coenzyme regeneration system(e.g. glucose and glucose dehydrogenase) and ES-ERED.
➢ All the ES-EREDs can be tested respectively in the reaction system above or with the ERED Screening Kit (SynKit ERED).
➢ All kinds of ES-EREDs corresponding to various optimum reaction conditions should be studied individually.
➢ High concentration Substrate or product with may inhibit ES-ERED’s activity. However, the inhibition can be relieved by batch addition of substrate.
Example 1(α,β-unsaturated aldehydes or ketones) (1):
Example 2(α,β-unsaturated carboxylic acids and their derivatives) (2):
Keep 2 years below -20℃.
Never contact with extreme conditions such as: high temperature, high/low pH and high concentration organic solvent.
1. Lucídio C, Fardelone J, Augusto R, e tal. J.Mol.Catal.B:Enzym., 2004, 29: 41-45.
2. Stueckler C, Hall M, Ehammer H, e tal. .Org.Lett, 2007, 9(26): 5409-5411.
Product detail pictures:
Related Product Guide:
To be the stage of realizing dreams of our employees! To build a happier, more united and more professional team! To reach a mutual benefit of our customers, suppliers, the society and ourselves for China Gold Supplier for Cdmo In Pharma - Ene reductase (ERED) – SyncoZymes , The product will supply to all over the world, such as: Kuwait, Egypt, Johor, We insist on "Quality First, Reputation First and Customer First". We are committed to providing high-quality products and good after-sales services. Up to now, our products have been exported to more than 60 countries and areas around the world, such as America, Australia and Europe. We enjoy a high reputation at home and abroad. Always persisting in the principle of "Credit, Customer and Quality", we expect cooperation with people in all walks of life for mutual benefits.
By Camille from Jamaica - 2017.10.27 12:12
This enterprise in the industry is strong and competitive, advancing with the times and develop sustainable, we are very pleased to have a opportunity to cooperate!
By Marcie Green from Lesotho - 2017.03.08 14:45
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