China Gold Supplier for Cdmo In Pharma - Ene reductase (ERED) – SyncoZymes

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China Gold Supplier for Cdmo In Pharma - Ene reductase (ERED) – SyncoZymes Detail:

ES-EREDs catalyze various substrate types because of wide spectrum of substrates. In general, the C=C of α, β -unsaturated compounds with electron-absorbing groups (including ketone aldehyde, nitro groups, carboxylic acids, esters, anhydride, lactones, imines, etc.) are easily reduced by ES-EREDs, but the unactivated double bonds not.

There are 46 kinds of ERED enzyme products (Number as ES-ERED-101~ES-ERED-146) developed by SyncoZymes.

Catalytic mechanism:

Ene reductase ERED1
Ene reductase ERED2

Enzymes	Product Code	Specification
Enzyme Powder	ES-ERED-101~ ES-ERED-146	a set of 46 Ene Reductases, 50 mg each 46 items * 50mg / item, or other quantity
Screening Kit (SynKit)	ES-ERED-4600	a set of 46 Ene Reductases, 50 mg each 46 items * 50mg / item, or other quantity

★ High substrate specificity.
★ Strong chiral selectivity.
★ High conversion.
★ Less by-products.
★ Mild reaction conditions.
★ Environmentally friendly.
★ High safety.

➢ Normally, the reaction system should include substrate, buffer solution (optimum reaction pH), coenzymes(NAD(H) or NADP(H) ), coenzyme regeneration system(e.g. glucose and glucose dehydrogenase) and ES-ERED.
➢ All the ES-EREDs can be tested respectively in the reaction system above or with the ERED Screening Kit (SynKit ERED).
➢ All kinds of ES-EREDs corresponding to various optimum reaction conditions should be studied individually.
➢ High concentration Substrate or product with may inhibit ES-ERED’s activity. However, the inhibition can be relieved by batch addition of substrate.

Example 1(α,β-unsaturated aldehydes or ketones)⁽¹⁾:

Ene reductase ERED3

Example 2(α,β-unsaturated carboxylic acids and their derivatives)⁽²⁾:

Ene reductase ERED4

Keep 2 years below -20℃.

Never contact with extreme conditions such as: high temperature, high/low pH and high concentration organic solvent.

1. Lucídio C, Fardelone J, Augusto R, e tal. J.Mol.Catal.B:Enzym., 2004, 29: 41-45.
2. Stueckler C, Hall M, Ehammer H, e tal. .Org.Lett, 2007, 9(26): 5409-5411.

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Our target should be to consolidate and improve the high-quality and repair of current goods, in the meantime regularly produce new solutions to meet unique customers' needs for China Gold Supplier for Cdmo In Pharma - Ene reductase (ERED) – SyncoZymes , The product will supply to all over the world, such as: Islamabad, Albania, South Africa, Most problems between suppliers and clients are due to poor communication. Culturally, suppliers can be reluctant to question things they do not understand. We break down those barriers to ensure you get what you want to the level you expect, when you want it. Faster delivery time and the product you want is our Criterion .

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