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Leading Manufacturer for Top Cdmo Companies 2020 - Imine reductase (IRED) – SyncoZymes

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Leading Manufacturer for Top Cdmo Companies 2020 - Imine reductase (IRED) – SyncoZymes Detail:

Imine reductase (IRED)

Enzymes Product Code Specification
Enzyme Powder ES-IRED-101~ ES-IRED-114 a set of 14 Imine Reductase, 50 mg each
96-Well Enzyme Screening Kit ES-IRED-1400 a set of 14 Imine Reductase, 1 mg each

★ High substrate specificity.
★ Strong chiral selectivity.
★ High conversion.
★ Less by-products.
★ Mild reaction conditions.
★ Environmentally friendly.

➢ Normally, the reaction system should include substrate, buffer solution, enzyme, coenzyme, and coenzyme regeneration system.
➢ All kinds of ES-IREDs corresponding to various optimum reaction conditions should be studied individually.
➢ High concentration Substrate or product with may inhibit ES-IRED’s activity. However, the inhibition can be relieved by batch addition of substrate.

Example 1(Biosynthesis of chiral 2-methyl pyrrolidine)(1):

Imine reductase (IRED)3

Example 2(Biosynthesis of secondary amine)(2):

Imine reductase (IRED)4

Example 3 (Reduction of Cyclic Imines)(3):

Imine reductase (IRED)5

Keep 2 years below -20℃.

Never contact with extreme conditions such as: high temperature, high/low pH and high concentration organic solvent.

1. Scheller PN, Fademrecht S, Hofelzer S, et al. ChemBioChem, 2014, 15, 2201-2204.
2. Wetzl D, Gand M, Ross A, et al. ChemCatChem, 2016, 8, 2023-2026.
3. Li H, Luan ZJ, Zheng GW, et al. Adv. Synth. Catal. 2015, 357, 1692-1696.


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  • The product classification is very detailed that can be very accurate to meet our demand, a professional wholesaler.
    5 Stars By Christopher Mabey from Costa rica - 2018.06.18 17:25
    This company has the idea of "better quality, lower processing costs, prices are more reasonable", so they have competitive product quality and price, that's the main reason we chose to cooperate.
    5 Stars By Gustave from California - 2018.08.12 12:27
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