Manufacturer for Oligonucleotide Cdmo - Oxynitrilases (HNL) – SyncoZymes

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Manufacturer for Oligonucleotide Cdmo - Oxynitrilases (HNL) – SyncoZymes Detail:

Oxynitrilases HNL

Enzymes	Product Code	Specification
Enzyme Powder	ES-HNL-101~ ES-HNL-129	a set of 29 oxynitrilases, 50 mg each 29 items * 50mg / item, or other quantity
Screening Kit (SynKit)	ES-HNL-1800	a set of 18 (S)-oxynitrilases, 1 mg each 18 items * 1mg / item
Screening Kit (SynKit)	ES-HNL-1100	a set of 11 (R)-oxynitrilases, 1 mg each 11items * 1mg / item

★ High substrate specificity.
★ Strong chiral selectivity.
★ High conversion.
★ Less by-products.
★ Mild reaction conditions.
★ Environmentally friendly.

➢ Normally, the reaction system should include substrate (aldehydes / ketones, HCN), buffer solution (optimum reaction pH) and the enzymes.
➢ All the ES-HNLs can be tested respectively in the reaction system above or with the HNL Screening Kit (SynKit HNL).
➢ All kinds of ES-HNLs corresponding to various optimum reaction conditions should be studied individually.
➢ High concentration Substrate or product with may inhibit ES-HNL’s activity. However, the inhibition can be relieved by batch addition of substrate.

Example 1⁽¹⁾:

Oxynitrilases HNL3

Keep 2 years below -20℃.

Never contact with extreme conditions such as: high temperature, high/low pH and high concentration organic solvent.

1 Langermann J, Guterl JK, Pohl M, e tal. Bioprocess Biosyst Eng, 2008, 31: 155-161.

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Cdmo Biopharma