Carboxylic acid reductase (CAR)
Short Description:
About Carboxylic acid reductase
ES-CAR (Carboxylic acid reductase): catalyzes the reduction of carboxyl group to aldehyde group. In the catalytic process, ATP activation and coenzyme NADPH are required as hydrogen transporters. There are 2 kinds of CAR enzyme products (Number as ES-CAR101~ ES-CAR-102) developed by SyncoZymes.
Catalytic reaction type:
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| Enzymes | Product Code | Specification |
| Screening Kit (SynKit) | ES-CAR-101-ES-CAR-102 | a set of 2 Ketoreductases, 1 mg each 2 items * 1mg / item |
★ High substrate specificity.
★ Strong chiral selectivity.
★ High conversion.
★ Less by-products.
★ Mild reaction conditions.
★ Environmentally friendly.
➢ Normally, the reaction system should include substrate, buffer solution, enzyme, coenzyme, ATP.
➢ CAR should be added last into reaction system, after the pH and temperature been adjusted to the reaction condition.
Example 1(Synthesis of cinnamyl alcohol from phenylalanine)(1):
Keep 2 years below -20℃.
Never contact with extreme conditions such as: high temperature, high/low pH and high concentration organic solvent.
1. Zhang, Chen, et al. Microbial cell factories 19.1 (2020): 1-10.
