Amine Dehydrogenase (AmDH)

Short Description:

About Amine Dehydrogenase

ES-AmDH (Amine Dehydrogenase): an enzyme that can catalyze the ammoniation of carbonyl group and reduce it to amino group. It is a coenzyme NADH dependent enzyme, and NADH acts as a hydrogen transmitter. There are 4 kinds of AmDH enzyme products (Number as ES-AmDH101~ES-AmDH104) developed by SyncoZymes, which can be used in regioselective or stereoselective reductive amination of aldehydes and ketones.

Catalytic reaction type:

About Amine Dehydrogenase2

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Product Detail

Product Tags

Product Information:



★ High substrate specificity.
★ Strong chiral selectivity.
★ High conversion.
★ Less by-products.
★ Mild reaction conditions.
★ Environmentally friendly.

Instructions for use:

➢ Normally, the reaction system should include substrate, buffer solution, enzyme, coenzyme and coenzyme regeneration system (e.g. glucose and glucose dehydrogenase).
➢ AmDH should be added last into reaction system, after the pH and temperature been adjusted to the reaction condition.

Application Examples:

Example 1(Synthesis of corresponding chiral amines by reductive amination of alkyl aryl ketones)(1):



Keep 2 years below -20℃.


Never contact with extreme conditions such as: high temperature, high/low pH and high concentration organic solvent.


1. Kong W, Liu Y, Huang C, et al. Angewandte Chemie International Edition, 2022: e202202264.

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