Glucose dehydrogenase (GDH)
Short Description:
About Glucose dehydrogenase
ES-GDH (Glucose dehydrogenase): GDH catalyze the dehydrogenation of glucose to produce gluconic acid (lactone), and reduce NAD(P)+ to NAD(P)H, with NAD(P)+ as electron receptor. GDH is often used for the regeneration of coenzyme NAD(P)H in biocatalysis fields with other main enzyme. There are 10 kinds of GDH enzyme products (ES-GDH-101~ES-GDH-110) developed by SyncoZymes, among which ES-GDH110 has the highest activity and is the mainly recommended GDH.
Catalytic reaction type:
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| Enzymes | Product Code | Specification |
| Enzyme Powder | ES-GDH-101~ ES-GDH-109 | 9 enzymes*50mg/pc, or other quantity |
★ High substrate specificity.
★ High conversion.
★ Less by-products.
★ Mild reaction conditions.
★ Environmentally friendly.
➢ Normally, the reaction system should include substrate, buffer solution, enzyme, and coenzyme.
➢ If GDH is used for coenzyme regeneration, the main enzyme is necessary, and the reaction system should be designed according to the main enzyme.
Example 1(Biocatalysis synthesis of imine to chiral amine with imine reductase)(1):
Keep 2 years below -20℃.
Never contact with extreme conditions such as: high temperature, high/low pH and high concentration organic solvent.
1. Bernhard L M, McLachlan J, Gröger H. Process Development of Enantioselective Imine Reductase-Catalyzed Syntheses of Pharmaceutically Relevant Pyrrolidines[J]. Organic Process Research & Development, 2022.
