Nitro reductase (NTR)

Short Description:

About nitro reductase

ES-NTRs: Are flavoenzymes that catalyze the NAD(P)H-dependent reduction of the nitro groups on nitroaromatic and nitroheterocyclic compounds to hydroxylamino and/or amino derivatives. They are widely used in organic synthesis of aromatic hydroxylamine and aromatic amine, tumor therapy, biological detection and the degradation of environmental pollutants. There are 12 kinds of Nitro reductase (NTR) products (Number as ES-NTR-101~ES-NTR-112) developed by SyncoZymes.

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Product Detail

Product Tags

About nitro reductase:

Catalytic reaction type:

Nitro reductase NTR2

Catalytic mechanism:

Nitro reductase NTR3

Product Information:

Nitro reductase NTR
Enzymes Product Code Specification
Enzyme Powder ES-NTR-101~ ES-NTR-112 a set of 12 Nitro Reductases, 50 mg each 12 items * 50mg / item, or other quantity
Screening Kit (SynKit) ES-NTR-1200 a set of 12 Nitro Reductases, 1 mg each 12 items * 1mg / item


★ Broad substrate spectrum.
★ High conversion.
★ Less by-products.
★ Mild reaction conditions.
★ Environmentally friendly.

Instructions for use:

➢ Normally, the reaction system should include substrate, buffer solution (optimum reaction pH), coenzymes (NAD(H) or NADP(H) ), coenzyme regeneration system(e.g. glucose and glucose dehydrogenase) and ES-NTR.
➢ All kinds of ES-NTRs corresponding to various optimum reaction conditions should be studied individually.
➢ ES-NTR should be added last into reaction system with optimum reaction pH and temperature.

Application Examples:

Example 1 (1):

Nitro reductase NTR4

Example 2 (2):

Nitro reductase NTR5


Keep 2 years below -20℃.


Never contact with extreme conditions such as: high temperature, high/low pH and high concentration organic solvent.


1 Dai R J, Chen J,Lin J, e tal. J Hazard Marer, 2009, 170, 141–143.
2 Betancor L, Berne C, Luckarift H R., e tal. Chem. Commun, 2006, 3640–3642.

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