Phenylalanine dehydrogenase (PDH)
|Enzyme Powder||ES-PDH-101~ ES-PDH-108||a set of 8 Nitrile Reductase, 50 mg each 8 items * 50mg / item, or other quantity|
★ High substrate specificity.
★ Strong chiral selectivity.
★ High conversion.
★ Less by-products.
★ Mild reaction conditions.
★ Environmentally friendly.
➢ Normally, the reaction system should include substrate, buffer solution, enzyme, coenzyme (NAD(H)), coenzyme regeneration system (e.g. ammonium formate and formate dehydrogenase).
➢ Each kind of ES-PDH corresponding to various optimum reaction conditions, which could be studied individually if needed.
➢ The ES-PDH should be added last into reaction system to maintain the activity.
Example 1(Biosynthesis of phenylalanine derivatives from phenylpyruvate derivatives)(1):
Keep 2 years below -20℃.
Never contact with extreme conditions such as: high temperature, high/low pH and high concentration organic solvent.
1. Francesca Paradisi, Stuart Collins, et al. Journal of Biotechnology, 2007, 128, 408–411.