Phenylalanine ammonia lyase (PAL)

Short Description:

About Phenylalanine ammonia lyase

ES-PAL: A class of enzymes that catalyze the direct deamination of L-phenylalanine to trans- cinnamic acid. Syncozymes developed 10 items of phenylalanine ammonia lyase (numbered ES-PAL-101~ES-PAL-110), which can be used in deamination or reverse reaction of phenylalanine and its derivatives.

Catalytic reaction type:

Phenylalanine ammonia lyase (PAL)2

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Product Detail

Product Tags

Product Information:

Phenylalanine ammonia lyase (PAL)
Enzymes Product Code Specification
Enzyme Powder ES-PAL-101~ ES-PAL-110 a set of 10 L-phenylalanine ammonia-lyase, 50 mg each 10 items * 50mg / item, or other quantity


★ High substrate specificity.
★ Strong chiral selectivity.
★ High conversion.
★ Less by-products.
★ Mild reaction conditions.
★ Environmentally friendly.

Instructions for use:

➢ Normally, the reaction system should include substrate, buffer solution and enzyme.
➢ Each kind of ES-PAL corresponding to various optimum reaction conditions, which could be studied individually.
➢ The ES-PAL should be added last into reaction system to maintain the activity.

Application Examples:

Example 1(Biosynthesis of trans cinnamic acid from phenylalanine) (1):

Phenylalanine ammonia lyase (PAL)3

Example 2(Biosynthesis of phenylalanine derivative from trans-cinnamic acid derivative)(2):

Phenylalanine ammonia lyase (PAL)4


Keep 2 years below -20℃.


Never contact with extreme conditions such as: high temperature, high/low pH and high concentration organic solvent.


1. Zachary Mays, Karishma Mohan, et al. Chem Commun (Camb). 2020, 56, 5255-5258.

2. Ian Rowles, Bas Groenendaal, et al. Tetrahedron, 2016. 72, 7343-7347.

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