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D-Amino acid dehydrogenase (D-AADH)
About D-Amino acid dehydrogenase
ES-D-AADH (D-Amino acid dehydrogenase): an enzyme that can reduce 2-keto acid into corresponding D-amino acid. The reaction need NADP(H) and inorganic ammonia donor (such as ammonia or ammonium ion). There are 17 kinds of D-amino acid dehydrogenases (Number as ES-DAADH-101~ ES-DAADH-117) developed by SyncoZymes.
Catalytic reaction type:
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Esterase&Lipase (PLE&CALB)
About Esterase&Lipase
ES-PLEs: A class of hydrolases that catalyze the formation and breakage of ester bonds. They can take part in many kinds of biochemical reactions, such as esterification, transesterification and hydrolysis. They are widely used in many fields such as food processing, chemical industry, biomedicine, chiral medicine and environmental treatment.
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E-Mail: lchen@syncozymes.com
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Epoxide hydrolase (EH)
About epoxide hydrolase
EH is ether hydrolase that catalyze the stereoselective hydrolysis of racemic epoxides to produce 1, 2-diol and optically active epoxides, which can be used for the chiral resolution of epoxides or the preparation of chiral diols. They are widely used in medicine and other fields. There are 3 kinds of epoxide hydrolases products (Number as ES-EH-101～ES-EH-103) developed by SyncoZymes. ES-EH is a useful tool to catalyze the synthesis of chiral alcohols through stereoselective hydrolysis of aliphatic and aromatic epoxides.
Catalytic reaction type:
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E-Mail: lchen@syncozymes.com
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Formate dehydrogenase (FDH)
About Formate dehydrogenase
ES-FDH (Formate dehydrogenase): FDH catalyze the dehydrogenation of ammonium formate to produce carbon dioxide and ammonia, and reduce NAD to NADH with NAD as electron receptor. FDH is often used for the regeneration of coenzyme NADH. There are 4 kinds of FDH enzyme products (ES-FDH-101~ES-FDH-104) developed by SyncoZymes, among which ES-FDH102 has the highest activity and is the mainly recommended FDH.
Catalytic reaction type:
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Glucose dehydrogenase (GDH)
About Glucose dehydrogenase
ES-GDH (Glucose dehydrogenase): GDH catalyze the dehydrogenation of glucose to produce gluconic acid (lactone), and reduce NAD(P)+ to NAD(P)H, with NAD(P)+ as electron receptor. GDH is often used for the regeneration of coenzyme NAD(P)H in biocatalysis fields with other main enzyme. There are 10 kinds of GDH enzyme products (ES-GDH-101~ES-GDH-110) developed by SyncoZymes, among which ES-GDH110 has the highest activity and is the mainly recommended GDH.
Catalytic reaction type:
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E-Mail: lchen@syncozymes.com
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Monoamine oxidase (MAO)
About Monoamine oxidase
ES-MAO(Monoamine oxidase): MAO catalyze the oxidative deamination of monoamines to produce hydrogen peroxide, ammonia and corresponding aldehydes. In the catalytic process, oxygen is necessary as oxidant. There are 6 kinds of MAO enzyme products (Number as ES-MAO-101～ES-MAO-106) developed by SyncoZymes, which can be used in the oxidative deamination of monoamine compounds.
Catalytic reaction type:
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E-Mail: lchen@syncozymes.com
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Lactate Dehydrogenase (LDH)
About Lactate dehydrogenase
There is 1 kind of LDH enzyme product (Number as ES-LDH) developed by SyncoZymes. LDH can catalyze the reduction of pyruvate to L-lactic acid, or reduction of other similar α-keto acids. In the process of catalysis, NADH is necessary as hydrogen transporter.
Lactate dehydrogenasecatalytic reaction type
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E-Mail: lchen@syncozymes.com
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Imine reductase (IRED)
About Imine reductase
ES-IRED: A class of enzymes that catalyze the reduction of C=N bond to C-N bond. It belongs to redox enzyme, with coenzyme NADPH for hydrogen transportation. According to the chiral preference of the products, they can be divided into R-IRED and S-IRED. Syncozymes developed 15 imine reductases (numbIRED ES-IRED-101-ES-IRED-115), which can be widely used in regioselective and stereoselective reduction of imines to prepare chiral amines.
Catalytic reaction type:
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E-Mail: lchen@syncozymes.com
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Nitrile reductase (NRED)
About Nitrile reductase
There is 3 kind of NRED enzyme product (Number as ES-NRED101~ ES-NRED103) developed by SyncoZymes. NRED can catalyze the reduction of nitrile group to amine. In the process of catalysis, NADPH is needed as hydrogen transporter.
Nitrile reductasecatalytic reaction type
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E-Mail: lchen@syncozymes.com
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Phenylalanine dehydrogenase (PDH)
About Phenylalanine dehydrogenase
ES-PDH: A class of oxidoreductase. The positive reaction can catalyze the oxidative deamination of L phenylalanine salt in the presence of NAD to produce phenylpyruvate salt, and the reverse reaction can catalyze the synthesis of corresponding amino acid salt from phenylpyruvate salt. Syncozymes developed 8 items of phenylalanine dehydrogenase (numbered ES-PDH-101~ES-PDH-108). ES-PDH can be used to prepare phenylalanine salt or corresponding amino acid salt from phenylpyruvic acid salt or derivatives.
Catalytic reaction type:
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E-Mail: lchen@syncozymes.com
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Leucine Dehydrogenase (LeuDH)
About Leucine dehydrogenase
There is 1 kind of LeuDH enzyme product (Number as ES-LeuDH-101) developed by SyncoZymes. LeuDH can catalyze the reductive ammoniation of 4-methylbutanoic acid (salt) to L-leucine or the oxidation of leucine to 4-methylbutanoic acid. ES-LeuDH can also catalyze the reductive amination of α-keto acids with similar structure to prepare corresponding amino acid derivatives. In the process of catalysis, NADH is necessary as hydrogen transporter.
Leucine dehydrogenasecatalytic reaction type
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E-Mail: lchen@syncozymes.com
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Threonine deaminase (TDA)
About Threonine deaminase
ES-TDA (Threonine deaminase): a pyridoxal phosphate protein that catalyzes the deamination of threonine to produce 2-ketobutyric acid and ammonia. Pyridoxal 5-phosphate is necessary as coenzyme in the catalytic system. There is only 1 kind of TDA enzyme product (Number as ES-TDA) developed by SyncoZymes, which can be used to prepare 2-ketobutyric acid or its derivatives from threonine.
Catalytic reaction type:
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E-Mail: lchen@syncozymes.com
